Win Game Combos

Doomsday + Laboratory Maniac: Use Doomsday to stack your library with specific cards that allow you to win the game. The last card you stack should be Laboratory Maniac. Cast Laboratory Maniac and then cast a spell that draws a card. With no cards left in your library, Laboratory Maniac’s ability triggers and you win the game.

Doomsday - Search your library and graveyard for five cards and exile the rest. Put the chosen cards on top of your library in any order. You lose half your life
Laboratory Maniac - If you would draw a card while your library has no cards in it
Laboratory Maniac

Pestilence + Personal Sanctuary: Use Pestilence to deal 1 damage to all creatures and players, but with Personal Sanctuary, you won’t take any damage, effectively destroying all creatures.

Pestilence - At the beginning of the end step
Personal Sanctuary - During your turn
Personal Sanctuary

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